Research

Evidence

Before any course is released through THIS WAY UP, it is rigorously tested in our research unit, Virtual Clinic. We have treated over 1,400 patients in Virtual Clinic, using versions of the depression, panic, social phobia, GAD, and transdiagnostic courses, and have found that the courses significantly reduce anxiety and depression. Virtual Clinic is also continually involved in a range of research projects investigating the nature, causes and treatment of anxiety disorders.

THIS WAY UP is the platform through which we make the research based programs available. As of October 2015, we had more than 4500 clinicians and more than 9700 patients enrolled in THIS WAY UP.

The degree of benefit gained from THIS WAY UP depends on the level to which people immerse themselves in the courses, and on how much they practice what they learn in each lesson. Three out of four people complete all the lessons, and three out of four who complete are no longer troubled by their emotional disorder. Nine out of ten say they are satisfied. Internationally, this is one of the strongest treatments for these conditions that is presently available.

Participate

Would you like to participate in our research? We need people who may experience mental health disorders.

Virtual Clinic is where we conduct our clinical trials for internet based education and treatment programs for anxiety and depression.

If you feel you might fit the criteria for our current studies, or just want to know more about how you can get involved, please visit the Virtual Clinic website.

You can make a valuable contribution to mental health research simply by sharing your experience, time and knowledge with our researchers.



GENERAL RESEARCH PAPERS

Adherence as a determinant of effectiveness of internet cognitive behavioural therapy for anxiety and depressive disorders. Hilvert-Bruce Z, Rossouw PJ, Wong N, Sunderland M, Andrews G. Behaviour Research and Therapy. 2012, 50(7-8): 463-468.

Available at: www.ncbi.nlm.nih.gov/pubmed/22659155

Investigating trajectories of change in psychological distress amongst patients with depression and generalised anxiety disorder treated with internet cognitive behavioural therapy. Sunderland M, Wong N, Hilvert-Bruce Z, Andrews G Behaviour Research and Therapy. 2012, 50(6): 374-380.

Available at: www.ncbi.nlm.nih.gov/pubmed/22498311

Is Internet treatment ready for prime time? Andrews G, Titov N. MJA 2010; 192 (11): S45-S47.

Available at: www.ncbi.nlm.nih.gov/pubmed/20528709

Characteristics of adults with anxiety or depression treated at an Internet clinic: Comparison with a national survey and an outpatient clinic. Titov N, Andrews G, Kemp A, Robinson E. PLoS ONE 2010, 5(5): e10885. doi:10.1371/journal.pone.0010885.

Available at: www.journals.plos.org/plosone/article?id=10.1371/journal.pone.0010885

Hit and Miss: Innovation and dissemination of evidence based psychological treatments. Andrews G, Titov N. Behaviour Research and Therapy 2009; 47:974-979.

Available at: www.ncbi.nlm.nih.gov/pubmed/19625014

OUR RESEARCH ABOUT DEPRESSION

A clinical audit of changes in suicide ideas with internet treatment for depression. Watts S, Newby J, Mewton L, Andrews G. British Medical Journal Open. 2012 2: e001558.

Available at: bmjopen.bmj.com/content/2/5/e001558

Internet treatment for depression: A randomized controlled trial comparing clinician vs. technician assistance. Titov N, Andrews G, Davies M, McIntyre K, Robinson E, Solley K. PLoS ONE 2010, 5(6): e10939. doi:10.1371/journal.pone.0010939.

Available at: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010939

Clinician-assisted Internet-based treatment is effective for depression: A randomized controlled trial. Perini S, Titov N, Andrews G. Australian and New Zealand Journal of Psychiatry. (2009). 43(6): 571-578.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/19440890

The Climate Sadness program: an open trial of Internet-based treatment for depression. Perini S, Titov N, Andrews G. Electronic Journal of Applied Psychology 2008; 4(2).

Available at: http://sensoria.swinburne.edu.au/index.php/sensoria/article/view/135

OUR RESEARCH ABOUT ANXIETY DISORDERS

Transdiagnostic Internet treatment for anxiety disorders: A randomized controlled trial. Titov N, Andrews G, Johnston L, Robinson E, Spence J. Behaviour Research and Therapy 2010. doi:10.1016/j.brat.2010.05.014

Available at: http://www.ncbi.nlm.nih.gov/pubmed/19440890

Effectiveness of transdiagnostic internet cognitive behavioural treatment for mixed anxiety and depression in primary care. Newby JM, Mewton L, Williams AD, Andrews G. Journal of Affective Disorders. 2014, 165: 45-52.

Available at: http://www.sciencedirect.com/science/article/pii/S0165032714002316

Internet cognitive behavioural therapy for mixed anxiety and depression: a randomized controlled trial and evidence of effectiveness in primary care. Newby JM, Mackenzie A, Williams AD, Mcintyre K, Watts S, Wong N, Andrews G. 2013, 43(12): 2635-2648.

Available at: http://www.sciencedirect.com.simsrad.net.ocs.mq.edu.au/science/article/pii/0887618594900019

OUR RESEARCH ABOUT GAD

The effectiveness of internet cognitive behavioural therapy for generalised anxiety disorder in clinical practice. Mewton L, Wong N, Andrews G Depression and Anxiety. 2012, 29(10): 843-849.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/22949296

Internet treatment for generalized anxiety disorder: A randomized controlled trial comparing clinician vs. technician assistance. Robinson E, Titov N, Andrews G, McIntyre K, Schwencke G, Solley K. PLoS ONE 2010, 5(6): e10942. doi:10.1371/journal.pone.0010942.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/20532167

Clinician-assisted internet treatment is effective for generalized anxiety disorder: randomized controlled trial. Titov N, Andrews G, Robinson E, Schwencke G, Johnston L, Solley K, Choi I. Australian and New Zealand Journal of Psychiatry 2009, 43:10, 905-912.

Available at: http://anp.sagepub.com/content/43/10/905

OUR RESEARCH ABOUT PANIC

Allen AR, Newby JM, Mackenzie A, Smith J, Boulton M, Loughnan SA, Andrews G. Internet cognitive behavioural treatment for panic disorder: a randomised controlled trial and evidence of effectiveness in primary care. British Journal of Psychiatry Open. 2016; 2: 154-162.

Available at:http://bjpo.rcpsych.org/content/2/2/154

Clinician-assisted Internet-based treatment is effective for panic: A randomized controlled trial. Wims E, Titov N, Andrews G, Choi I. Australian and New Zealand Journal of Psychiatry 2010; 44:599-607.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/20560847

The Climate Panic program: an open trial of Internet-based treatment for panic disorder. Wims E, Titov N, Andrews G. Electronic Journal of Applied Psychology 2008; 4(2).

Available at: http://ojs.lib.swin.edu.au/index.php/ejap/article/view/134

OUR RESEARCH ABOUT SOCIAL PHOBIA

Internet treatment for social phobia reduces comorbidity. Titov N, Gibson M, Andrews G, McEvoy P. Australian and New Zealand Journal of Psychiatry 2009; 43:754-9.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/19629797

An RCT comparing effect of two types of support on severity of symptoms for people completing Internet-based cognitive behaviour therapy for social phobia. Titov N, Andrews G, Schwencke G, Solley K, Johnston L, Robinson E. Australian and New Zealand Journal of Psychiatry 2009; 43:10,920 — 926.

Available at: http://anp.sagepub.com/content/43/10/920

Randomized controlled trial of web-based treatment of social phobia without clinician guidance. Titov N, Andrews G, Choi I, Schwencke G, Johnston L. Australian and New Zealand Journal of Psychiatry 2009; 43:913 — 919.

Available at: http://anp.sagepub.com/content/43/10/913

The Shyness Program: Longer Term Benefits, Cost-Effectiveness, and Acceptability. Titov, N., G. Andrews, et al. Australian & New Zealand Journal of Psychiatry 2009; 43: 36-44.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/19085526

Shyness 5: The clinical effectiveness of Internet-based clinician-assisted treatment of social phobia. Aydos L R, Titov N, Andrews G. Australasian Psychiatry 2009; 17:488-492.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/20001373

Shyness 3: An RCT of guided vs unguided internet based CBT for social phobia. Titov N, Andrews G, Choi I, Schwencke G, Mahoney A. Australian & New Zealand Journal of Psychiatry 2008; 42:1030-1040.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/19016091

Shyness 2: Treating social phobia online: replication and extension. Titov N, Andrews G, Schwencke G. Australian and New Zealand Journal of Psychiatry 2008; 42:595-605.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/18612863

Shyness 1: Distance treatment for social over the Internet. A randomized controlled trial. Titov N, Andrews G, Schwencke G, Drobny J, Einstein D. Australian & New Zealand Journal of Psychiatry 2008; 42:585-594.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/18612862

Characteristics of adults with anxiety or depression treated at an Internet clinic: Comparison with a national survey and an outpatient clinic. Titov N, Andrews G, Kemp A, Robinson E. PLoS ONE 2010, 5(5): e10885. doi:10.1371/journal.pone.0010885.

Available at: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010885

OUR RESEARCH ABOUT OCD

Grisham JR, Williams AD. Responding to intrusions in obsessive-compulsive disorder: The roles of neuropsychological functioning and beliefs about thoughts. Journal of Behavior Therapy and Experimental Psychiatry. 2013; 44: 343-350.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/23501288

Mahoney A, Andrews G. Internet-based cognitive behaviour therapy for obsessive compulsive dsorder. In: Crowe E, O’Dell AR, editors. Obessive-Compulsive Disorder: Symptoms, Prevalence and Psychological Treatments: Nova; 2014.

Mahoney AEJ, Mackenzie A, Williams AD, Smith J, Andrews G. Internet cognitive behavioural treatment for obsessive compulsive disorder: A randomised controlled trial. Behaviour Research and Therapy. 2014; 63: 99-106.

Available at: http://www.ncbi.nlm.nih.gov/pubmed/25461784